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Fast- (green) and slow (red)-twitch muscle fibers

Cellular localization of zyxin and Akt (Chan et al Cell Death Differ 2007 14: 1688)

Liver glycogen (Periodic acid–Schiff staining) (Chan et al EMBO Rep 2011 12:847)

Gene expression profiling (microarray) (Chan et al Chem Biol 2015 22: 355)

White adipose tissue (H&E staining) (Tse et al Diabetes 2017 66: 1858)

Proliferating mammary epithelial cells (PCNA staining) (Chan et al 2010 EMBO J 29: 956)

Mammary gland morphology (Carmine staining) (Chan et al 2010 EMBO J 29: 956)

Amount of cyclin D1 in mammary gland (immunoblotting) (Chan et al 2010 EMBO J 29: 956)

Middle cerebral artery occlusion (MCAO)-induced brain damage in mouse (triphenyl-tetrazolium chloride staining) (Chan et al J Neurosci 2011 31: 8083)

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Mammary gland development (Carmine staining) (Chan et al EMBO J 2010 29: 956)

Glucagon (red) and insulin (green) in Islet of Langerhans (Chan et al Diabetes 2010 59: 883)

Apoptosis of mouse embryonic fibroblast (DAPI staining) (Tse et al Mol Cell Biol 2013 33: 1797)

Stat5a in HC11 cell (Chan et al 2010 EMBO J 29: 956)

Glucose tolerance test (Tse et al Diabetes 2017 66: 1858)

Mitochondria in muscle (Electron microscopy)

Brain morphology of PIKE knockout mice (Chan et al J Neuosci 2011 31: 8083)

Primary adipocytes (Tse et al Mol Cell Biol 2013 33: 1797)

Functional roles of PIKE-A

Invasion of K562 cells in spleen (CD45 staining) (Chan et al Oncogene 2009 28: 3825)

Mouse hippocampal neuron (Chan et al EMBO J 2011 30: 4274)

Glucagon (green) and insulin (red) in Islet of Langerhans (Chan et al Diabetes 2010 59: 883)

Electroencephalography (EEG) of mouse after seizue induction (Chan et al Adv Biol Regul 2012 52: 66)

Distribution of GluR2 in mouse hippocampal neuron (Chan et al EMBO J 2011 30: 4274)

Absence of milk spot in newborn PIKE-/- mouse (Chan et al EMBO J 2010 29: 956)

Lipid accumulation in mouse liver after high fat-diet feeding (H&E staining) (Chan et al Chem Biol 2015 22: 355)

Islet of Langerhans in mouse pancreas (Chan et al Diabetes 2010 59: 883)

Milk protein analysis in PIKE knockout mice (Chan et al EMBO J 2010 29: 956)

Brown adipose tissue (H&E staining) (Chan et al Chem Biol 2015 22: 355)

Mouse oligodendrocyte (Chan et al PNAS 2014 111: 1993)

Extracellular flux analysis (Tse et al Diabetes 2017 66: 1858)

Cortical neuron (Golgi staining) (Chan et al J Neuosci 2011 31: 8083)

Stroke-induced brain damage in mouse (Silver staining) (Chan et al Adv Biol Regul 2012 52: 66)

Proliferating oligodendrocytes in corpus callosum (Chan et al PNAS 2014 111: 1993)

Lysolecithin-Induced Focal demyelination in mouse corpus callosum (Chan et al PNAS 2014 111: 1993)

GluR2 distribution in mouse hippocampal neuron (Chan et al EMBO J 2011 30: 4274)

Body weight of PIKE knockout mice

Cortex of E13 mouse embryo (Chan et al J Neuosci 2011 31: 8083)